N-Boc-2-Amino-4-formylthiazole

Name: N-Boc-2-Amino-4-formylthiazole
Brand: ChemScene
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CAS No. 494769-34-5
Cat. No. CS-W006822
Purity≥95%
MDL No.MFCD08275704

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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N-Boc-2-Amino-4-formylthiazole|CS-W006822

Structure of 494769-34-5

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Description

N-Boc-2-Amino-4-formylthiazole features a masked amine and a reactive aldehyde group, enabling direct incorporation into diverse heterocyclic scaffolds. This bench-stable, moisture-tolerant building block facilitates efficient access to thiazole-based libraries through one-pot condensation and cyclization protocols under standard conditions.

Application

N-Boc-2-Amino-4-formylthiazole serves as a versatile building block for the synthesis of thiazole-based heterocycles, enabling efficient access to medicinally relevant scaffolds. The Boc-protected amine and formyl group offer orthogonal reactivity, facilitating sequential functionalization in multistep syntheses. Its bench-stable nature and compatibility with standard coupling and cyclization conditions make it well-suited for both academic and industrial R&D workflows.

General Information

CAS No. 494769-34-5
Cat. No. CS-W006822
Purity ≥95%
MDL No. MFCD08275704
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₂N₂O₃S
Molecular Weight 228.27
Synonym(s) Tert-butyl 4-formylthiazol-2-ylcarbamate
SMILES O=C(OC(C)(C)C)NC1=NC(C=O)=CS1

Computational Chemistry Data

TPSA 68.29
LogP 2.3026
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Aldehyde

Building Blocks Skeleton Aliphatic heterocycle compounds Thiazolidine compounds

Key Words

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N-Boc-2-Amino-4-formylthiazole

CAS No. 494769-34-5

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