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tert-Butyl N-[5-(hydroxymethyl)-1,3-thiazol-2-yl]carbamate

  • CAS No. 1001419-37-9

  • Cat. No. CS-0036054
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-[5-(hydroxymethyl)-1,3-thiazol-2-yl]carbamate|CS-0036054

Structure of 1001419-37-9

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General Information

  • CAS No. 1001419-37-9
  • Cat. No. CS-0036054
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄N₂O₃S
  • Molecular Weight 230.28
  • Synonym(s) Tert-butyl 5-(hydroxymethyl)thiazol-2-ylcarbamate
  • SMILES CC(C)(C)OC(=O)NC1=NC=C(CO)S1

Description

tert-Butyl N-[5-(hydroxymethyl)-1,3-thiazol-2-yl]carbamate features a hydroxymethyl-functionalized thiazole core paired with a stable tert-butyl carbamate protecting group. This combination enables direct incorporation into complex heterocyclic scaffolds, offering enhanced solubility and compatibility in synthetic workflows involving nucleophilic substitution or metal-catalyzed coupling reactions.

Application

tert-Butyl N-[5-(hydroxymethyl)-1,3-thiazol-2-yl]carbamate serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the hydroxymethyl position. The protected amine and reactive thiazole core offer orthogonal handles for downstream transformations. Its bench-stable nature and compatibility with standard coupling and oxidation protocols facilitate efficient access to diverse thiazole-containing scaffolds in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   71.45
  • LogP   1.9824
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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