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CS-W001157 4
Total: USD 88.00

(2-Methyl-2H-indazol-6-yl)boronic acid

  • CAS No. 1001907-57-8

  • Cat. No. CS-0053516
  • Molecule weight175.98
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Methyl-2H-indazol-6-yl)boronic acid|CS-0053516

Structure of 1001907-57-8

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General Information

  • CAS No. 1001907-57-8
  • Cat. No. CS-0053516
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BN₂O₂
  • Molecular Weight 175.98
  • Synonym(s) 6-Borono-2-methyl-2H-indazole
  • SMILES CN1C=C2C=CC(=CC2=N1)B(O)O

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, enabling efficient access to biologically active indazolyl scaffolds. The methyl group enhances stability and modulates electronic properties, while the pendant boronic acid facilitates reliable functionalization under standard conditions.

Application

(2-Methyl-2H-indazol-6-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds prevalent in medicinal chemistry. The boronic acid moiety exhibits good bench stability and tolerates a range of functional groups, facilitating direct incorporation into complex heterocyclic frameworks. Its utility is enhanced by predictable reactivity and straightforward purification, making it well-suited for iterative synthesis and library generation in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   -0.7469
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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