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Structure of 1002328-44-0
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This trifluoromethyl-substituted diazirine derivative integrates a photoreactive 3H-diazirin-3-yl group at the para position of a phenyl ring, enabling site-specific protein crosslinking upon UV irradiation. The pendant propanoic acid moiety facilitates conjugation to biomolecules via standard amide coupling protocols. Designed for bioorthogonal labeling applications, it exhibits enhanced stability under ambient conditions and tolerates aqueous environments.
3-(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)propanoic acid serves as a photoreactive building block for covalent probe development, enabling site-specific labeling upon UV irradiation. The trifluoromethyl-substituted diazirine moiety exhibits enhanced stability and reactivity under physiological conditions, while the para-phenylpropanoic acid scaffold provides a versatile handle for conjugation and integration into bioactive molecules. Functions effectively in affinity labeling workflows and is compatible with standard purification methods.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅱ
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Hazard Statements : H228-H315-H319
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Precautionary Statements : P210-P240-P241-P264-P280-P302+P352-P362+P364-P370+P378
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Lot numbers can be found on the outside label of a product: