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Structure of 73899-14-6
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3-Phenyl-3-(trifluoromethyl)-3H-diazirine is a bench-stable, moisture-tolerant photoaffinity label featuring a highly reactive diazirine ring. This trifluoromethyl-substituted aryl diazirine integrates readily into bioconjugation workflows, enabling site-specific protein crosslinking upon UV irradiation. The electron-withdrawing trifluoromethyl group enhances photolysis efficiency while stabilizing the carbene intermediate formed during activation.
3-Phenyl-3-(trifluoromethyl)-3H-diazirine serves as a stable, bench-compatible photoaffinity labeling agent, enabling site-specific covalent capture of interacting biomolecules upon UV irradiation. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the diazirine ring undergoes efficient photolysis to generate reactive carbene intermediates. This compound facilitates targeted protein-ligand interaction studies and is compatible with diverse biological matrices and downstream analytical workflows.
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅱ
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Hazard Statements : H226-H314-H318
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Precautionary Statements : P210-P240-P242-P243-P264-P271-P280-P301+P330+P331-P304+P340-P363-P370+P378-P501
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Lot numbers can be found on the outside label of a product: