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Structure of 1003298-87-0
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2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol features a boronate ester group flanked by two chlorine substituents, enabling efficient Suzuki-Miyaura coupling. The tetramethylcyclopentadienone-derived boronate enhances stability and reactivity under standard conditions. This phenolic boronate integrates readily into complex molecular architectures with minimal side reactions.
2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pinacol boronate group enables stable, air-tolerant handling and broad functional group compatibility. The dichlorophenol core facilitates direct coupling at the 4-position while preserving orthogonality for downstream transformations. This reagent is particularly valuable in constructing substituted heterocycles and complex scaffolds common in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: