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Structure of 1004294-77-2
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This trifluoromethyl ketone integrates a boronate ester handle for efficient cross-coupling, enabling direct access to fluorinated aryl ketones under standard conditions. The sterically protected tetramethylboronate moiety ensures high stability and compatibility with diverse reaction environments.
2,2,2-Trifluoro-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-one serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl ketone moiety provides enhanced metabolic stability and modulates lipophilicity, while the pinacol borane group enables efficient, mild coupling with aryl and heteroaryl halides. This compound exhibits excellent bench stability, facilitates straightforward purification, and supports scalable synthesis of fluorinated biaryl architectures relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: