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CS-W001157 4
Total: USD 88.00

1,2-Dichloro-3-fluoro-4-nitrobenzene

  • CAS No. 100465-04-1

  • Cat. No. CS-0683455
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,2-Dichloro-3-fluoro-4-nitrobenzene|CS-0683455

Structure of 100465-04-1

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Description

1,2-Dichloro-3-fluoro-4-nitrobenzene features a highly functionalized aromatic core with orthogonal reactivity. The para-nitro group enables electrophilic substitution cascades, while the ortho-dichloro and fluoro substituents provide steric and electronic modulation. This compound serves as a key scaffold in heterocyclic synthesis and advanced materials chemistry.

Application

1,2-Dichloro-3-fluoro-4-nitrobenzene serves as a versatile building block in heterocyclic synthesis and medicinal chemistry. Its orthogonal halogenation pattern enables sequential Pd-catalyzed cross-coupling reactions, while the nitro group facilitates reduction and subsequent functionalization. The molecule exhibits excellent bench stability and compatibility with standard reaction conditions, enabling efficient access to substituted aryl scaffolds used in API development.

General Information

  • CAS No. 100465-04-1
  • Cat. No. CS-0683455
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Cl₂FNO₂
  • Molecular Weight 209.99
  • Synonym(s) None
  • SMILES C1=CC(=C(C(=C1[N+](=O)[O-])F)Cl)Cl

Computational Chemistry Data

  • TPSA   43.14
  • LogP   3.0407
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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