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Structure of 345-18-6
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5-Chloro-2-fluoronitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted aromatic scaffolds. Its orthogonal reactivity profile—where the chloro and fluoro groups facilitate selective Suzuki-Miyaura and Buchwald-Hartwig couplings—supports modular assembly of complex heterocycles. The nitro group provides a handle for reduction to aniline intermediates, while the molecule exhibits good bench stability and ease of purification, making it well-suited for multi-step synthetic sequences in industrial R&D workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: