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Structure of 100683-08-7
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1-Methoxycyclopropanecarboxylic acid features a strained cyclopropyl ring fused to a carboxylic acid and methoxy group, delivering high reactivity in cycloaddition and functionalization reactions. The electron-withdrawing nature of the ester moiety enhances electrophilicity at the carbonyl carbon, enabling efficient coupling with nucleophiles under mild conditions. This bench-stable derivative serves as a valuable building block for synthesizing bioactive heterocycles and pharmaceutical intermediates.
1-Methoxycyclopropanecarboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of cyclopropyl-containing scaffolds via standard ester transformations and decarboxylation protocols. Its constrained ring structure imparts enhanced metabolic stability and conformational rigidity, facilitating targeted ligand design. The molecule exhibits good bench stability and is compatible with common functional group manipulations, including nucleophilic substitution and hydrogenation.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: