2,6-Dichloro-3-nitropyridin-4-amine

Name: 2,6-Dichloro-3-nitropyridin-4-amine
Brand: ChemScene
Availability: InStock
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CAS No. 2897-43-0
Cat. No. CS-W003036
Purity≥98%
MDL No.MFCD03265754

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2,6-Dichloro-3-nitropyridin-4-amine|CS-W003036

Structure of 2897-43-0

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Description

2,6-Dichloro-3-nitropyridin-4-amine features a pyridine core bearing two chlorine substituents and a nitro group at C3, with an amine functionality at C4. This electron-deficient heterocycle integrates readily into cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive nitrogen-containing compounds.

Application

2,6-Dichloro-3-nitropyridin-4-amine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine scaffolds via nucleophilic displacement and subsequent reduction. The dichloro substitution pattern facilitates sequential functionalization, while the nitro and amino groups provide orthogonal reactivity for downstream transformations. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for medicinal chemistry campaigns and process-scale applications.

General Information

CAS No. 2897-43-0
Cat. No. CS-W003036
Purity ≥98%
MDL No. MFCD03265754
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃Cl₂N₃O₂
Molecular Weight 208.00
Synonym(s) 4-pyridinamine, 2,6-dichloro-3-nitro-
SMILES O=[N+]([O-])C1=C(N)C=C(Cl)N=C1Cl

Computational Chemistry Data

TPSA 82.05
LogP 1.8788
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,6-Dichloro-3-nitropyridin-4-amine

CAS No. 2897-43-0

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