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3,3-Difluoropropan-1-amine hydrochloride

  • CAS No. 1010097-89-8

  • Cat. No. CS-0112580
  • Purity≥95%
  • MDL No.MFCD12024563

*For research and further manufacturing use only, not for direct human use.

3,3-Difluoropropan-1-amine hydrochloride|CS-0112580

Structure of 1010097-89-8

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General Information

  • CAS No. 1010097-89-8
  • Cat. No. CS-0112580
  • Purity ≥95%
  • MDL No. MFCD12024563
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₈ClF₂N
  • Molecular Weight 131.55
  • Synonym(s) None
  • SMILES NCCC(F)F.[H]Cl

Description

This difluorinated amine hydrochloride delivers a stable, moisture-tolerant building block for bioactive molecule synthesis. The electron-deficient alkyl chain enhances reactivity in nucleophilic substitution, enabling efficient incorporation into pharmaceutical scaffolds and functional polymers under standard conditions.

Application

3,3-Difluoropropan-1-amine hydrochloride serves as a versatile building block for fluorinated amine synthesis, enabling efficient incorporation of the difluoromethyl group into bioactive scaffolds. Its stability under standard handling conditions and compatibility with amide coupling, reductive amination, and nucleophilic substitution reactions make it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.0221
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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