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Structure of 101166-65-8
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tert-Butyl(2-iodoethoxy)dimethylsilane serves as a robust, moisture-tolerant protecting group for alcohols, enabling selective functionalization in complex synthesis. The iodoethoxy moiety facilitates efficient coupling reactions, while the bulky tert-butyl group ensures stability under basic conditions and minimizes side reactions.
tert-Butyl(2-iodoethoxy)dimethylsilane serves as a robust, bench-stable protecting group for alcohols, enabling selective mono-etherification under mild conditions. The iodoethyl side chain facilitates subsequent functionalization via palladium-catalyzed cross-coupling reactions, offering a versatile handle for late-stage diversification in complex molecule synthesis. Its compatibility with a broad range of reaction conditions and ease of removal under mild acidic or fluoride-mediated cleavage makes it ideal for iterative synthetic sequences in medicinal chemistry and natural product synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: