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CS-W001157 4
Total: USD 88.00

2,6-Dibromobenzyl alcohol

  • CAS No. 1013031-65-6

  • Cat. No. CS-M3140
  • Molecule weight265.93
  • Purity≥98%
  • MDL No.MFCD13185492

*For research and further manufacturing use only, not for direct human use.

2,6-Dibromobenzyl alcohol|CS-M3140

Structure of 1013031-65-6

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General Information

  • CAS No. 1013031-65-6
  • Cat. No. CS-M3140
  • Purity ≥98%
  • MDL No. MFCD13185492
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆Br₂O
  • Molecular Weight 265.93
  • Synonym(s) (2,6-Dibromophenyl)methanol
  • SMILES BrC1=C(CO)C(Br)=CC=C1

Description

2,6-Dibromobenzyl alcohol features two bromine atoms positioned at the 2 and 6 positions of the benzyl ring, imparting high electrophilicity and enhanced stability under standard conditions. This dibrominated scaffold integrates readily into cross-coupling reactions and serves as a robust building block for functionalized aromatic systems in medicinal chemistry and materials science.

Application

2,6-Dibromobenzyl alcohol serves as a versatile building block in synthetic organic chemistry, enabling the construction of brominated aromatic scaffolds via electrophilic substitution or cross-coupling reactions. The benzyl alcohol functionality facilitates straightforward derivatization—such as oxidation to aldehydes or esterification—while the geminal dibromo substitution provides orthogonal reactivity for palladium-catalyzed transformations. Its bench-stable crystalline form and compatibility with standard purification methods make it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Ema, Tadashi; Tanida, Daisuke; Matsukawa, Tatsuya; Sakai, Takashi Chemical Communications, 2008 , # 8 p. 957 - 959
  • Route2
    • 1,3-Dibromo-2-(chloromethyl)benzene|CS-0617567
      858006-31-2
    • ~%
    • In-stock
      2,6-Dibromobenzyl alcohol|CS-M3140
      1013031-65-6

    References

    • Olivier Recueil des Travaux Chimiques des Pays-Bas, 1926 , vol. 45, p. 303
  • Route3

    References

    • Olivier Recueil des Travaux Chimiques des Pays-Bas, 1926 , vol. 45, p. 303

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.7039
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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