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CS-W001157 4
Total: USD 88.00

8-Nitroquinoline-7-carbaldehyde

  • CAS No. 101327-87-1

  • Cat. No. CS-0131621
  • Purity≥95%
  • MDL No.MFCD08436438
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

8-Nitroquinoline-7-carbaldehyde|CS-0131621

Structure of 101327-87-1

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Description

8-Nitroquinoline-7-carbaldehyde delivers a potent electron-deficient scaffold for conjugate addition and transition-metal-catalyzed coupling reactions. The para-nitro group enhances electrophilicity at the aldehyde, enabling efficient C–C bond formation under mild conditions. This bench-stable reagent integrates readily into complex molecular architectures with high functional group tolerance.

Application

8-Nitroquinoline-7-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling the construction of quinoline-based scaffolds through standard coupling and functional group transformation protocols. Its electron-deficient quinoline core enhances reactivity in nucleophilic additions, while the aldehyde functionality facilitates imine formation and conjugate addition reactions. Bench-stable and readily purified by column chromatography, it supports efficient synthesis of heterocyclic libraries and API intermediates.

General Information

  • CAS No. 101327-87-1
  • Cat. No. CS-0131621
  • Purity ≥95%
  • MDL No. MFCD08436438
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆N₂O₃
  • Molecular Weight 202.17
  • Synonym(s) 8-Nitro-7-quinolinecarboxaldehyde
  • SMILES O=CC1=CC=C2C=CC=NC2=C1[N+]([O-])=O

Computational Chemistry Data

  • TPSA   73.1
  • LogP   1.9555
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H341
Precautionary Statements : P264-P280-P302+P352-P362-P405-P501

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