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CS-W001157 4
Total: USD 88.00

Benzo[b]thiophene-4-carbaldehyde

  • CAS No. 10133-25-2

  • Cat. No. CS-0097674
  • Purity≥97%
  • MDL No.MFCD18432490

*For research and further manufacturing use only, not for direct human use.

Benzo[b]thiophene-4-carbaldehyde|CS-0097674

Structure of 10133-25-2

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General Information

  • CAS No. 10133-25-2
  • Cat. No. CS-0097674
  • Purity ≥97%
  • MDL No. MFCD18432490
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆OS
  • Molecular Weight 162.21
  • Synonym(s) Benzo[b]thiophene-4-carboxaldehyde
  • SMILES O=CC1=C(C=CS2)C2=CC=C1

Description

Benzo[b]thiophene-4-carbaldehyde features a fused heterocyclic core with a reactive aldehyde handle at the 4-position. This electron-deficient scaffold integrates readily into synthetic routes requiring planar, π-rich architectures. The aldehyde group enables efficient coupling reactions and functionalization under mild conditions, making it valuable for constructing advanced organic materials and pharmaceutical intermediates.

Application

Benzo[b]thiophene-4-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to biologically relevant scaffolds. Its aldehyde functionality facilitates nucleophilic addition, reductive amination, and coupling reactions with minimal side reactivity. The molecule exhibits excellent bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.7138
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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