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Structure of 1083197-78-7
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4-(Trifluoromethyl)nicotinaldehyde features a trifluoromethyl group at the pyridine ring's 4-position, enhancing electron-withdrawing character and metabolic stability. This aldehyde integrates readily into synthetic scaffolds, serving as a key building block for pharmaceutical intermediates and functional materials under standard conditions.
4-(Trifluoromethyl)nicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via condensation and coupling reactions. Its electron-deficient pyridine ring enhances reactivity in nucleophilic additions, while the aldehyde functionality facilitates straightforward derivatization. The trifluoromethyl group imparts metabolic stability and improved lipophilicity, making this compound valuable for constructing bioactive molecules with enhanced pharmacokinetic profiles.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H317-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: