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Structure of 10138-32-6
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Ethyl bicyclo[2.2.1]hept-5-ene-2-carboxylate features a rigid, strained cyclohexadienyl framework with a conjugated double bond and an ester-functionalized bridgehead position. This structural motif delivers high reactivity in Diels-Alder cycloadditions, enabling rapid access to complex polycyclic architectures under mild conditions. The molecule exhibits excellent thermal stability and predictable regioselectivity, making it ideal for synthetic applications requiring precise stereochemical control.
Ethyl bicyclo[2.2.1]hept-5-ene-2-carboxylate serves as a versatile bicyclic building block in synthetic organic chemistry, enabling efficient access to strained carbocyclic frameworks. Its rigid norbornene core supports Diels-Alder cycloadditions and functional group transformations with predictable stereochemistry. The ester moiety facilitates selective derivatization, while the exocyclic double bond provides reactivity for hydrogenation, oxidation, or metal-catalyzed coupling. Bench-stable and readily purified by column chromatography, it functions as a key intermediate in natural product synthesis and medicinal chemistry campaigns requiring conformationally constrained scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: