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CS-W001157 4
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(S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine

  • CAS No. 101403-24-1

  • Cat. No. CS-M1301
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine|CS-M1301

Structure of 101403-24-1

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General Information

  • CAS No. 101403-24-1
  • Cat. No. CS-M1301
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₁NO
  • Molecular Weight 219.32
  • Synonym(s) (S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-2-Naphthalenamine(Rotigotine)
  • SMILES COC1=C(CC[C@@H]2NCCC)C(C2)=CC=C1

Synthesis

  • Route1
    • 5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride|CS-0341636
      3904-24-3
    • ~96%
    • (S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine|CS-M1301
      101403-24-1

    References

    • KANDULA, Mahesh Patent: WO2013/168033 A1, 2013 ; Location in patent: Paragraph 0099; 00100 ;
  • Route2
    • null|null
      1222074-03-4
    • ~98%
    • (S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine|CS-M1301
      101403-24-1

    References

    • Marquillas Olondriz, Francisco; Pomares Marco, Marta Patent: US2011/152543 A1, 2011 ; Location in patent: Page/Page column 3 ;
  • Route3
    • null|null
      101403-23-0
    • ~85%
    • (S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine|CS-M1301
      101403-24-1

    References

    • Seiler, Max P.; Stoll, Andre P.; Closse, Annemarie; Frick, Willy; Jaton, Annelise; Vigouret, Jean-Marie Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 912 - 917

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   2.5521
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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