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Structure of 101421-15-2
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2-Iodo-5-nitrobenzonitrile features a nitro group and nitrile moiety flanking an iodine atom on a benzene ring, enabling direct coupling in cross-coupling reactions. This electron-deficient aryl iodide integrates readily into complex scaffolds under standard conditions.
2-Iodo-5-nitrobenzonitrile serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of biaryl and heteroaryl scaffolds under Pd-catalyzed conditions. The iodide group facilitates reliable C–C bond formation, while the nitro and nitrile functionalities provide orthogonal reactivity for downstream transformations. Its stability under standard reaction conditions and compatibility with diverse coupling partners make it well-suited for medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: