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CS-W001157 4
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4-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

  • CAS No. 1014613-05-8

  • Cat. No. CS-D0733
  • Purity≥97%
  • MDL No.MFCD13191645

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine|CS-D0733

Structure of 1014613-05-8

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General Information

  • CAS No. 1014613-05-8
  • Cat. No. CS-D0733
  • Purity ≥97%
  • MDL No. MFCD13191645
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₁BrN₂O₂S
  • Molecular Weight 351.22
  • Synonym(s) 4-Bromo-2-methyl-1-phenylsulfonyl-7-azaindole
  • SMILES O=S(N1C2=NC=CC(Br)=C2C=C1C)(C3=CC=CC=C3)=O

Synthesis

  • Route1
    • In-stock
      4-Bromo-1-benzenesulfonyl-7-azaindole|CS-B0524
      889939-25-7
    • null|null
      74-88-4
    • ~82%
    • In-stock
      4-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine|CS-D0733
      1014613-05-8

    References

    • Liddle, John; Bamborough, Paul; Barker, Michael D.; Campos, Sebastien; Cousins, Rick P.C.; Cutler, Geoffrey J.; Hobbs, Heather; Holmes, Duncan S.; Ioannou, Chris; Mellor, Geoff W.; Morse, Mary A.; Payne, Jeremy J.; Pritchard, John M.; Smith, Kathryn J.; Tape, Daniel T.; Whitworth, Caroline; Williamson, Richard A. Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 9 p. 2504 - 2508
  • Route2
    • null|null
      74-88-4
    • ~79%
    • In-stock
      4-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine|CS-D0733
      1014613-05-8

    References

    • GLAXO GROUP LIMITED Patent: WO2008/34860 A1, 2008 ; Location in patent: Page/Page column 111-112 ; WO 2008/034860 A1
  • Route3
    • null|null
      98-09-9
    • ~%
    • In-stock
      4-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine|CS-D0733
      1014613-05-8

    References

    • GLAXO WELLCOME MANUFACTURING PTE LTD; CHEN, Deborah, W.; DUNCAN, Sarah; KING, Nigel, Paul; LEE, Kiew, Ching; MAK, Sing, Yeung; RIVERS, Dean, Andrews Patent: WO2012/170752 A1, 2012 ; WO 2012/170752 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.96
  • LogP   3.34422
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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