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Structure of 1015610-31-7
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4-Chloro-5-iodo-1H-pyrrolo[2,3-b]pyridine is a halogenated heterocycle featuring complementary reactive sites for cross-coupling. The chlorine and iodine substituents enable sequential functionalization under palladium catalysis. This scaffold integrates readily into complex molecular architectures with defined regiochemistry.
4-Chloro-5-iodo-1H-pyrrolo[2,3-b]pyridine serves as a versatile building block for constructing biologically relevant heterocycles via palladium-catalyzed cross-coupling reactions. The ortho-halogen substitution pattern enables sequential functionalization, with the chloro group participating in Suzuki-Miyaura or Buchwald-Hartwig couplings, while the iodo moiety offers high reactivity in Stille and Negishi transformations. Bench-stable and amenable to purification by flash chromatography, it facilitates efficient access to complex pyrrolopyridine scaffolds in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: