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Structure of 1015868-48-0
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This pyrazole carboxylic acid features a 4-chlorophenyl substituent and a methyl group at the N1 position, delivering enhanced electron-withdrawing character. The para-chloroaryl moiety imparts favorable lipophilicity and metabolic stability, while the carboxylic acid enables direct conjugation or derivatization in medicinal chemistry campaigns.
3-(4-Chlorophenyl)-1-methyl-1H-pyrazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its defined regiochemistry and bench-stable carboxylic acid functionality facilitate direct derivatization, amidation, or esterification in synthetic workflows. The 4-chlorophenyl substituent provides a handle for further cross-coupling, while the methylpyrazole core offers predictable electronic and steric properties suitable for target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: