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Structure of 1017273-59-4
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This imidazo[2,1-b]thiazole derivative features a methyl-substituted imidazole ring fused to a thiazole core, delivering enhanced electron density and metabolic stability. The carboxylic acid group enables direct conjugation or derivatization in synthetic routes. This scaffold serves as a rigid, planar building block for bioactive heterocycles in medicinal chemistry applications.
3-Methylimidazo[2,1-b]thiazole-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its fused imidazo-thiazole core provides enhanced rigidity and polarity, enabling efficient incorporation into bioactive scaffolds. The carboxylic acid functionality facilitates direct derivatization via amide coupling or esterification, while the methyl group enhances solubility and metabolic stability. Bench-stable and readily purified by recrystallization, it functions reliably in standard peptide and macrocycle synthesis workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: