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Structure of 1018828-72-2
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8-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid features a rigid fused heterocyclic core bearing a strongly electron-withdrawing trifluoromethyl group and a carboxylic acid functionality. This combination imparts enhanced solubility in polar solvents and facilitates direct conjugation in medicinal chemistry applications. The molecule exhibits bench-stable handling characteristics and serves as a key scaffold for targeted ligand development.
8-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid enables direct conjugation or derivatization. The scaffold exhibits robust bench stability and compatibility with standard coupling reactions, facilitating rapid access to diverse analogs in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P280-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: