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Structure of 1020635-54-4
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2-Methoxy-5-nitronicotinic acid features a nitro group at the para position relative to the carboxylic acid, enhancing electrophilicity for cross-coupling reactions. The methoxy substituent provides steric and electronic modulation, improving solubility and stability under standard conditions. This derivative serves as a key building block in synthesizing bioactive heterocycles and functionalized pharmaceutical intermediates.
2-Methoxy-5-nitronicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of functionalized heterocycles and bioactive scaffolds. Its ortho-methoxy and meta-nitro substituents provide complementary reactivity for selective transformations, including palladium-catalyzed couplings and controlled reduction sequences. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: