Azetidin-3-amine dihydrochloride

Name: Azetidin-3-amine dihydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 102065-89-4
Cat. No. CS-W022573
Purity≥97%
MDL No.MFCD09910173

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Azetidin-3-amine dihydrochloride|CS-W022573

Structure of 102065-89-4

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Description

Azetidin-3-amine dihydrochloride offers a highly reactive, bench-stable amine handle for synthetic applications. This strained four-membered ring system integrates readily into diverse molecular architectures, enabling efficient access to bioactive compounds. The dihydrochloride salt form enhances solubility and handling in aqueous and polar organic media, streamlining incorporation into peptide analogs, kinase inhibitors, and functionalized polymers under standard conditions.

Application

Azetidin-3-amine dihydrochloride serves as a versatile synthetic building block for medicinal chemistry, enabling efficient access to saturated nitrogen heterocycles. The compound exhibits excellent bench stability and facilitates straightforward incorporation into diverse scaffolds via standard amine functionalization. Its high solubility and ease of purification support scalable synthesis, making it well-suited for constructing bioactive molecules, including kinase inhibitors and CNS-targeted compounds.

General Information

CAS No. 102065-89-4
Cat. No. CS-W022573
Purity ≥97%
MDL No. MFCD09910173
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₁₀Cl₂N₂
Molecular Weight 145.03
Synonym(s) amino-3 azetidine dichlorhydrate
SMILES NC1CNC1.[H]Cl.[H]Cl

Computational Chemistry Data

TPSA 38.05
LogP -0.2395
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Azetidine compounds

Key Words

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Azetidin-3-amine dihydrochloride

CAS No. 102065-89-4

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