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Structure of 1021860-94-5
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This boronate moiety features a trifluoromethyl group that enhances electron-withdrawing character and stability, while the methyl substituent improves solubility and steric profile. Designed for Suzuki-Miyaura cross-coupling, it enables efficient C–C bond formation under standard conditions with high functional group tolerance.
[4-Methyl-2-(trifluoromethyl)phenyl]boronic acid is a stable, bench-ready boronic acid that facilitates Suzuki-Miyaura cross-coupling reactions with high efficiency. Its electron-deficient aryl framework enhances reactivity toward palladium-catalyzed coupling, enabling the construction of complex biaryl architectures. The trifluoromethyl and methyl substituents provide orthogonal functional group handles for downstream derivatization, while the boronic acid moiety offers excellent compatibility with standard purification protocols and reaction conditions in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: