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Structure of 957034-45-6
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This boronic acid features a trifluoromethyl group that enhances electron deficiency and metabolic stability, enabling efficient Suzuki-Miyaura coupling under standard conditions. The ortho-methyl substituent improves solubility and reduces protodeboronation, offering robust performance in synthetic transformations.
(2-Methyl-4-(trifluoromethyl)phenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the boronic acid functionality offers excellent bench stability and compatibility with standard Suzuki-Miyaura coupling protocols. The methyl substituent provides steric control and modulates electronic properties, making it particularly valuable for medicinal chemistry and materials science applications requiring targeted molecular diversity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: