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Structure of 10235-65-1
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4,6-Dichloro-2-(pyridin-2-yl)pyrimidine is a bench-stable heterocyclic scaffold featuring two chlorine substituents at electron-deficient positions, enabling efficient coupling in cross-coupling reactions. The pyridin-2-yl group enhances solubility and directs regioselective functionalization, making it a robust building block for advanced pharmaceutical intermediates and agrochemicals.
4,6-Dichloro-2-(pyridin-2-yl)pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. The dichloropyrimidine core exhibits high reactivity toward nucleophiles, facilitating the installation of diverse aryl and heteroaryl substituents under mild conditions. Its bench-stable nature and compatibility with common functional groups make it ideal for parallel synthesis campaigns and API intermediate development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: