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Structure of 102732-63-8
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3-Pyrazolylacetic acid integrates a pyrazole heterocycle with a carboxylic acid side chain, enabling direct functionalization at the 3-position. This scaffold delivers enhanced solubility and stability in aqueous systems while supporting efficient coupling reactions under mild conditions. The molecule features a rigid, planar pyrazole ring that facilitates π-stacking interactions in supramolecular assemblies.
3-Pyrazolylacetic acid serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-containing heterocycles via standard coupling and functionalization reactions. Its carboxylic acid functionality facilitates direct amidation, esterification, and derivatization under mild conditions, while the pyrazole ring offers robust metabolic stability and hydrogen-bonding capacity. The compound exhibits excellent bench stability and is readily purified by recrystallization or chromatography, making it ideal for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: