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Potassium ((benzyloxy)methyl)trifluoroborate

  • CAS No. 1027642-25-6

  • Cat. No. CS-0156215
  • Purity≥97%
  • MDL No.MFCD11052815

*For research and further manufacturing use only, not for direct human use.

Potassium ((benzyloxy)methyl)trifluoroborate|CS-0156215

Structure of 1027642-25-6

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General Information

  • CAS No. 1027642-25-6
  • Cat. No. CS-0156215
  • Purity ≥97%
  • MDL No. MFCD11052815
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BF₃KO
  • Molecular Weight 228.06
  • Synonym(s) Potassium trifluoro[(phenylmethoxy)methyl]borate
  • SMILES C1=CC=C(C=C1)COC[B-](F)(F)F.[K+]

Description

Potassium ((benzyloxy)methyl)trifluoroborate delivers a stable, bench-ready boronate handle for Suzuki-Miyaura cross-coupling. The benzyloxy-methyl group enables selective protection and orthogonal reactivity, while the trifluoroborate moiety ensures high functional group tolerance and ease of handling under standard conditions.

Application

Potassium ((benzyloxy)methyl)trifluoroborate serves as a stable, bench-ready boron source for Suzuki-Miyaura cross-coupling reactions. It enables efficient formation of biaryl and heteroaryl scaffolds with excellent functional group tolerance. The benzyloxymethyl group enhances solubility and stability, while the trifluoroborate moiety facilitates reliable C–C bond formation under standard catalytic conditions. Ideal for late-stage functionalization in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   -0.4062
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   4

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