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Structure of 102808-02-6
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5-(Trifluoromethyl)-1H-imidazole-2-carbaldehyde features a trifluoromethyl group at the C5 position and an aldehyde function at C2, creating a highly electron-deficient imidazole scaffold. This combination enhances reactivity in nucleophilic addition and cycloaddition processes. The molecule exhibits excellent bench stability and solubility in common organic solvents, enabling straightforward incorporation into synthetic workflows for pharmaceutical intermediates and functional materials.
5-(Trifluoromethyl)-1H-imidazole-2-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of imidazole-based pharmacophores. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the aldehyde functionality facilitates efficient coupling reactions via reductive amination, condensation, or nucleophilic addition. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for high-throughput library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: