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1-Methyl-1H-pyrazole-3-carbaldehyde

  • CAS No. 27258-32-8

  • Cat. No. CS-W004820
  • Purity≥98%
  • MDL No.MFCD03419800
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-pyrazole-3-carbaldehyde|CS-W004820

Structure of 27258-32-8

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Description

1-Methyl-1H-pyrazole-3-carbaldehyde features a pyrazole ring bearing a methyl group at the N1 position and a formyl substituent at C3, delivering a polar, electron-deficient heterocyclic scaffold. This configuration enables direct integration into medicinal chemistry campaigns, particularly as a building block for bioactive molecules requiring hydrogen-bond acceptor capacity and metabolic stability. The aldehyde functionality supports efficient coupling reactions under mild conditions.

Application

1-Methyl-1H-pyrazole-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds via nucleophilic addition and condensation reactions. Its aldehyde functionality exhibits excellent stability under standard bench conditions and tolerates diverse functional groups, facilitating straightforward purification and integration into multi-step syntheses. The molecule functions effectively in coupling protocols and acts as a key intermediate in the construction of bioactive compounds.

General Information

  • CAS No. 27258-32-8
  • Cat. No. CS-W004820
  • Purity ≥98%
  • MDL No. MFCD03419800
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂O
  • Molecular Weight None
  • Synonym(s) 1H-pyrazole-3-carboxaldehyde, 1-methyl-
  • SMILES C[N]1C=CC(=N1)C=O

Computational Chemistry Data

  • TPSA   34.89
  • LogP   0.2326
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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