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CS-W001157 4
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4-Pyridin-4-yl-butyric acid

  • CAS No. 102878-73-9

  • Cat. No. CS-0059802
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Pyridin-4-yl-butyric acid|CS-0059802

Structure of 102878-73-9

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General Information

  • CAS No. 102878-73-9
  • Cat. No. CS-0059802
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) 4-Pyridinebutanoic acid
  • SMILES C(CC1=CC=NC=C1)CC(=O)O

Description

4-Pyridin-4-yl-butyric acid features a conjugated pyridine ring linked via a butyric acid side chain, enabling integration into bioactive scaffolds. The electron-rich pyridyl moiety enhances π-stacking interactions, while the carboxylic acid group facilitates derivatization and metal coordination. This structural combination supports applications in medicinal chemistry and materials design under standard conditions.

Application

4-Pyridin-4-yl-butyric acid serves as a versatile building block for constructing bioactive heterocyclic scaffolds and pharmaceutical intermediates. Its conjugated pyridyl-aliphatic carboxylic acid architecture enables straightforward derivatization via amide, ester, or amidation reactions, offering excellent functional group tolerance and bench stability. This compound functions effectively in standard coupling protocols and supports the synthesis of targeted molecules in medicinal chemistry workflows.

Synthesis

  • Route1
    • 4-(Pyridin-4-yl)butanenitrile|CS-0117758
      84200-09-9
    • ~%
    • In-stock
      4-Pyridin-4-yl-butyric acid|CS-0059802
      102878-73-9

    References

    • Menghin, Sonja; Pertz, Heinz H.; Kramer, Kai; Seifert, Roland; Schunack, Walter; Elz, Sigurd Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5458 - 5470
  • Route2

    References

    • Menghin, Sonja; Pertz, Heinz H.; Kramer, Kai; Seifert, Roland; Schunack, Walter; Elz, Sigurd Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5458 - 5470
  • Route3
    • null|null
      5264-02-8
    • ~%
    • In-stock
      4-Pyridin-4-yl-butyric acid|CS-0059802
      102878-73-9

    References

    • Menghin, Sonja; Pertz, Heinz H.; Kramer, Kai; Seifert, Roland; Schunack, Walter; Elz, Sigurd Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5458 - 5470

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.4889
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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