(S)-Methyl 2,3-dihydroxypropanoate

Name: (S)-Methyl 2,3-dihydroxypropanoate
Brand: ChemScene
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CAS No. 10303-88-5
Cat. No. CS-W000794
Purity≥96%
MDL No.MFCD14636488

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(S)-Methyl 2,3-dihydroxypropanoate|CS-W000794

Structure of 10303-88-5

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Description

(S)-Methyl 2,3-dihydroxypropanoate is a chiral diol ester featuring adjacent hydroxyl groups on a prochiral carbon backbone. This bench-stable derivative serves as a key building block in carbohydrate chemistry and asymmetric synthesis, where its defined stereochemistry enables selective transformations. The methyl ester moiety enhances solubility and stability under standard conditions, facilitating integration into complex synthetic sequences.

Application

(S)-Methyl 2,3-dihydroxypropanoate serves as a key chiral building block for the synthesis of bioactive molecules and natural product analogs. Its well-defined stereochemistry and two adjacent hydroxyl groups enable selective derivatization in glycosylation and phosphorylation reactions. The compound exhibits excellent bench stability, ease of purification, and compatibility with standard protecting group strategies, making it a reliable reagent in carbohydrate chemistry and medicinal intermediate development.

General Information

CAS No. 10303-88-5
Cat. No. CS-W000794
Purity ≥96%
MDL No. MFCD14636488
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₈O₄
Molecular Weight 120.10
Synonym(s) Methyl L-(+)-glycerate
SMILES COC(=O)[C@@H](O)CO

Computational Chemistry Data

TPSA 66.76
LogP -1.4874
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Fatty chain compounds

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(S)-Methyl 2,3-dihydroxypropanoate

CAS No. 10303-88-5

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