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Structure of 1032452-86-0
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This 3-(2-chloropyridin-4-yl)-1-methylindole features a chloropyridine moiety paired with a methylated indole core, enabling efficient integration into kinase inhibitor scaffolds. The electron-deficient pyridine ring enhances target binding affinity, while the N-methylindole offers favorable solubility and metabolic stability under standard conditions.
3-(2-Chloropyridin-4-yl)-1-methylindole serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The chloropyridine moiety facilitates reliable C–N and C–C bond formation, while the indole core provides a rigid, planar scaffold suitable for target-directed synthesis. Bench-stable and amenable to standard purification methods, it functions effectively in diversification campaigns for kinase inhibitors and other bioactive heterocycles.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: