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CS-W001157 4
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2-Amino-6-(methoxycarbonyl)benzoic acid

  • CAS No. 103259-06-9

  • Cat. No. CS-0370469
  • Molecule weight195.17
  • Purity95+%
  • MDL No.MFCD08690065

*For research and further manufacturing use only, not for direct human use.

2-Amino-6-(methoxycarbonyl)benzoic acid|CS-0370469

Structure of 103259-06-9

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General Information

  • CAS No. 103259-06-9
  • Cat. No. CS-0370469
  • Purity 95+%
  • MDL No. MFCD08690065
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₄
  • Molecular Weight 195.17
  • Synonym(s) ApreMilast-002
  • SMILES O=C(C1=CC=CC(N)=C1C(O)=O)OC

Synthesis

  • Route1

    References

    • Rogers, Miriam E.; Averill, Bruce A. Journal of Organic Chemistry, 1986 , vol. 51, # 17 p. 3308 - 3314
  • Route2
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      67-56-1
    • 3-Aminophthalic acid|CS-M2811
      5434-20-8
    • ~%
    • 2-Amino-6-(methoxycarbonyl)benzoic acid|CS-0370469
      103259-06-9

    References

    • NOVARTIS AG; BAETTIG, Urs; BRUCE, Ian; PRESS, Neil John; WATSON, Simon James Patent: WO2010/63802 A1, 2010 ; Location in patent: Page/Page column 45 ; WO 2010/063802 A1
  • Route3

    References

    • Rogers, Miriam E.; Averill, Bruce A. Journal of Organic Chemistry, 1986 , vol. 51, # 17 p. 3308 - 3314

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   89.62
  • LogP   0.7536
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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