2,5-Dibromo-4-fluoropyridine

Name: 2,5-Dibromo-4-fluoropyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1033203-46-1
Cat. No. CS-0162675
Purity≥97%
MDL No.MFCD11100660

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1033203-46-1

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Description

2,5-Dibromo-4-fluoropyridine features a fluorinated pyridine core with bromine substituents at the 2 and 5 positions, enabling efficient cross-coupling transformations. The electron-deficient aromatic ring pairs well with palladium catalysts, while the ortho-bromine atoms provide regioselective functionalization pathways. This compound serves as a key building block in medicinal chemistry and materials synthesis, offering high reactivity under standard conditions.

Application

2,5-Dibromo-4-fluoropyridine serves as a versatile building block for the synthesis of functionalized pyridine derivatives, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The fluorine and bromine substituents provide complementary sites for sequential functionalization, facilitating access to complex heterocyclic scaffolds. Its bench-stable nature and compatibility with standard coupling conditions make it well-suited for medicinal chemistry and process development workflows.

General Information

CAS No. 1033203-46-1
Cat. No. CS-0162675
Purity ≥97%
MDL No. MFCD11100660
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂Br₂FN
Molecular Weight None
Synonym(s) None
SMILES FC1=CC(Br)=NC=C1Br

Computational Chemistry Data

TPSA 12.89
LogP 2.7457
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,5-Dibromo-4-fluoropyridine

CAS No. 1033203-46-1

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