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CS-W001157 4
Total: USD 88.00

2,5-Dibromopyridine

  • CAS No. 624-28-2

  • Cat. No. CS-W001991
  • Purity≥98%
  • MDL No.MFCD00006221
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromopyridine|CS-W001991

Structure of 624-28-2

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Description

2,5-Dibromopyridine serves as a pivotal building block in heterocyclic synthesis, featuring two bromine substituents at electron-deficient positions on the pyridine ring. This configuration enables efficient palladium-catalyzed cross-coupling reactions, facilitating rapid access to substituted pyridines under standard conditions. The molecule exhibits excellent stability and handles well in air and moisture, simplifying integration into complex synthetic sequences.

Application

2,5-Dibromopyridine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. The bromine substituents exhibit high reactivity in Suzuki, Stille, and Negishi couplings, with excellent functional group tolerance and bench stability. Its orthogonal reactivity profile facilitates sequential transformations in complex molecule assembly, making it a reliable reagent for medicinal chemistry and materials science applications.

General Information

  • CAS No. 624-28-2
  • Cat. No. CS-W001991
  • Purity ≥98%
  • MDL No. MFCD00006221
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃Br₂N
  • Molecular Weight 236.89
  • Synonym(s) None
  • SMILES BrC1=CN=C(Br)C=C1

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.6066
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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