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Structure of 103977-79-3
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3-Bromo-2,4-difluoroaniline features a strategically positioned bromine atom flanked by two fluorine substituents, enabling selective coupling reactions in medicinal chemistry. This electron-deficient aniline derivative integrates readily into complex scaffolds under standard conditions, offering enhanced reactivity and stability for advanced synthetic applications.
3-Bromo-2,4-difluoroaniline serves as a valuable building block for pharmaceutical and agrochemical synthesis, enabling direct incorporation of bromo- and difluoro-substituted aryl scaffolds. Its reactivity profile supports palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig aminations, with excellent functional group tolerance. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: