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CS-W001157 4
Total: USD 88.00

2-(4-Aminophenyl)ethanol

  • CAS No. 104-10-9

  • Cat. No. CS-W005059
  • Purity≥95%
  • MDL No.MFCD00007922

*For research and further manufacturing use only, not for direct human use.

2-(4-Aminophenyl)ethanol|CS-W005059

Structure of 104-10-9

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General Information

  • CAS No. 104-10-9
  • Cat. No. CS-W005059
  • Purity ≥95%
  • MDL No. MFCD00007922
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) None
  • SMILES OCCC1=CC=C(N)C=C1

Description

4-Aminophenethyl alcohol has been used:as nonsymmetric monomer in the preparation of ordered [head-to-head (H-H) or tail-to-tail (T-T)] poly(amide-ester)in the synthesis of 4-aminostyrenein functionalization of graphene nanoplatelets

Application

2-(4-Aminophenyl)ethanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of diverse aryl-ether and amine-containing scaffolds. Its phenolic hydroxyl group allows for straightforward derivatization via etherification or esterification, while the primary amine facilitates coupling reactions, including amidation and reductive amination. The molecule exhibits good bench stability and is readily purified by recrystallization or chromatography, making it well-suited for high-throughput screening campaigns and process development workflows.

Synthesis

  • Route1

    References

    • Lee, Jung Gyu; Choi, Kyung Il; Koh, Hun Yeong; Kim, Youseung; Kang, Yonghan; Cho, Yong Seo Synthesis, 2001 , # 1 p. 81 - 84
  • Route2

    References

    • Bodnar, Brian S.; Vogt, Paul F. Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2598 - 2600
  • Route3
    • null|null
      1081-79-4
    • ~82%
    • In-stock
      2-(4-Aminophenyl)ethanol|CS-W005059
      104-10-9

    References

    • Schul'Tsev Russian Journal of General Chemistry, 2011 , vol. 81, # 11 p. 2300 - 2303

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.8036
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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