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CS-W001157 4
Total: USD 88.00

2,3-Bis((tert-butoxycarbonyl)amino)propanoic acid

  • CAS No. 104010-92-6

  • Cat. No. CS-0166811
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3-Bis((tert-butoxycarbonyl)amino)propanoic acid|CS-0166811

Structure of 104010-92-6

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General Information

  • CAS No. 104010-92-6
  • Cat. No. CS-0166811
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄N₂O₆
  • Molecular Weight 304.34
  • Synonym(s) N,N'-Bis-Boc-2,3-diaMinopropionic acid
  • SMILES O=C(O)C(CNC(OC(C)(C)C)=O)NC(OC(C)(C)C)=O

Description

This protected dipeptide building block features two tert-butoxycarbonyl groups that ensure stability and ease of handling during peptide synthesis. The bis-protected proline analog integrates cleanly into solid-phase workflows, enabling efficient access to complex peptide architectures under standard conditions.

Application

2,3-Bis((tert-butoxycarbonyl)amino)propanoic acid serves as a versatile dipeptide building block for solid-phase peptide synthesis, offering orthogonal protection of both α-amino and side-chain amine functionalities. Its tert-butyl carbamate groups provide excellent stability under basic conditions and facilitate selective deprotection during sequence elongation. The molecule enables efficient access to complex peptide scaffolds with minimal epimerization, making it ideal for the synthesis of bioactive peptides and peptidomimetics.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P403-P405-P501

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Computational Chemistry Data

  • TPSA   113.96
  • LogP   1.489
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   4

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