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Structure of 1040281-86-4
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Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate features a boronate ester group flanked by sterically protected tetramethylcyclopentadienone moieties, enabling stable coupling in Suzuki-Miyaura reactions. The thiophene core provides electron-rich character, while the methyl ester facilitates downstream derivatization. This bench-stable reagent integrates efficiently into complex molecule synthesis under standard conditions.
Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. Its stable tetramethylboronate group enables efficient C–C bond formation under mild conditions, with excellent functional group tolerance and bench stability. The methyl ester facilitates downstream derivatization, making it ideal for constructing thiophene-based heterocycles in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: