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Structure of 683229-61-0
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1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole delivers a boronate-functionalized indole scaffold with enhanced stability and compatibility in cross-coupling reactions. The tetramethyl-substituted dioxaborolane moiety enables reliable Suzuki-Miyaura coupling under mild conditions. This bench-stable reagent integrates readily into complex molecular architectures, offering efficient access to biologically relevant heterocycles.
1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole serves as a versatile boronate building block for Suzuki–Miyaura cross-coupling reactions. The tetramethylboronate moiety offers excellent stability, mild handling requirements, and broad functional group tolerance, enabling efficient C–C bond formation under standard catalytic conditions. Its indole core provides a privileged scaffold for medicinal chemistry applications, facilitating the rapid assembly of biologically relevant heterocyclic architectures with predictable regiochemistry and high yields.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: