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Structure of 10442-03-2
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4-(Prop-2-yn-1-yl)thiomorpholine 1,1-dioxide features a reactive alkyne handle tethered to a sulfonamide-containing heterocycle. This combination enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating site-specific conjugation in chemical biology and materials science applications. The molecule exhibits excellent stability under standard conditions and compatibility with aqueous environments.
4-(Prop-2-yn-1-yl)thiomorpholine 1,1-dioxide serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized heterocycles via copper-catalyzed azide-alkyne cycloaddition (CuAAC). The terminal alkyne functionality supports robust conjugation reactions with azides under mild conditions, while the sulfonamide group enhances solubility and provides a polar handle for downstream derivatization. Bench-stable and readily purified by standard chromatography, it functions effectively in modular synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: