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Structure of 1044851-76-4
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This boronate-functionalized pyrazole integrates readily into Suzuki-Miyaura coupling reactions under standard conditions. The dimethyl-substituted dioxaborolane moiety enhances stability and moisture tolerance, enabling reliable cross-coupling with aryl halides. Its bench-stable nature simplifies handling in synthetic workflows.
5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-methyl-1H-pyrazole serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The 1-methylpyrazole core provides enhanced solubility and functional group tolerance, while the pinacol boronate moiety enables efficient coupling with aryl and vinyl halides under mild conditions. This reagent facilitates rapid assembly of biologically relevant heterocyclic scaffolds with predictable regiochemistry and high yields, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: