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Structure of 1046831-98-4
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This boronate-functionalized pyrazole integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, delivering trifluoromethyl-substituted biaryls with high efficiency. The tetramethylborolane moiety ensures excellent stability and ease of handling, while the electron-deficient pyrazole core enhances reactivity in cross-coupling protocols.
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(trifluoromethyl)-1H-pyrazole serves as a robust boronate building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the tetramethylboronate moiety ensures excellent bench stability, high functional group tolerance, and ease of purification. It enables efficient late-stage diversification in medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: