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Structure of 1049730-39-3
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This pyrazole derivative features a fluorinated ethyl side chain and a boronate ester group, enabling direct coupling in Suzuki-Miyaura reactions. The tetramethyl-dioxaborolane moiety ensures stability and reactivity under standard conditions, while the 2-fluoroethyl substituent enhances metabolic resistance and modulates electronic properties for downstream functionalization.
1-(2-Fluoroethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole core provides metabolic stability and hydrogen-bonding capacity, while the 2-fluoroethyl side chain enables downstream functionalization via nucleophilic substitution. The pinacol boronate group offers excellent bench stability, ease of purification, and compatibility with a broad range of coupling partners under standard catalytic conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: