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Structure of 105391-70-6
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5-Bromo-6-fluoro-1H-indazole features a uniquely activated heterocyclic core with orthogonal halogen substituents enabling selective cross-coupling. This electron-deficient scaffold integrates readily into bioactive molecules, offering enhanced metabolic stability and tunable solubility for medicinal chemistry applications.
5-Bromo-6-fluoro-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo and fluoro substituents facilitate sequential functionalization, while the indazole core provides metabolic stability and favorable binding interactions in kinase inhibitors and other bioactive scaffolds. Its bench-stable crystalline form simplifies handling and purification in multi-step synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: